THE LAST LINE OF DEFENSE AGAINST SURGICAL SITE INFECTIONS
SURGX® is a powerful antimicrobial gel designed to reduce surgical site and post-surgical infections by destroying planktonic and biofilm encased bacteria. Using Next Science’s patented, non-toxic XBIO® technology, SURGX conforms to post-operative wounds to prevent surface attachment of free-floating bacteria, eliminate pathogens in the gel and defend against recolonization.
Product Features
- Sustained efficacy up to 5 days56
- Up to 7 log reduction within 2 minutes57
- Non-toxic
- Broad spectrum efficacy57
Mechanism of Action
SURGX uses patented XBIO Technology to attack biofilm structures, breaking the strong metallic bonds that hold the EPS together. This exposes the bacteria within the biofilm and makes them more vulnerable to attack and eradication. Bacteria that are enveloped within the biofilm disruption technology then experience cell lysis through a high osmolarity imbalance across the bacterial cell membrane and wall. XBIO Technology’s broad-spectrum efficacy helps defend from biofilm reformation.
Product Efficacy
Studies show SURGX provides broad-spectrum efficacy and multi-log biofilm reduction of MRSA and P. aeruginosa.
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Competitive Comparison
SURGX demonstrates up to 5-day efficacy in preventing MRSA bacterial growths.
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Clinical and Scientific Evidence
Stevenson, P. Myntti, M. (2020). SurgX® in the role of SSSI prevention: Clinical Observations Supporting the Integration of Antibiofilm Strategy into Surgical Incision Management. Jacksonville, FL: Next Science.
Kim D, Namen W, Moore J, Buchanan M, Hayes V, Myntti M, Hakaim
A. Clinical Assessment of a Biofilm-disrupting Agent for the Management of Chronic Wounds Compared With Standard of Care: A Therapeutic Approach. Wounds. Epub 2018.
Wolcott R. Disrupting the biofilm matrix improves wound healing outcomes. Journal of wound care. 2015 Aug;24(8):366-71.
Miller KG, Tran PL, Haley CL, et al. Next science wound gel technology, a novel agent that inhibits biofilm development by gram-positive and gram-negative wound pathogens. Antimicrob Agents Chemother. 2014;58(6):3060–3072.
Compatibility
*It is not recommended to be used with silver dressing as SURGX will deactivate the silver, however, the combination does not pose a risk to the patient.
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Product Q&A
Learn more about SURGX Antimicrobial Gel
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