The last line of defense against Surgical Site Infections

SurgX antimicrobial gel is designed to reduce surgical site
and post-surgical infections by destroying planktonic and
biofilm-encased bacteria. The proprietary, non-toxic formulation
conforms to the post-operative wound to provide proven
broad spectrum and sustained effectiveness for up to 5 days

Destroy Infectious Agents within SurgX

Leveraging Next Science’s proprietary Xbio technology, the comprehensive formulation kills pathogens enveloped within the gel by creating a high osmolarity environment coupled with a surfactant to induce cell lysis. The unique mechanism of action has broad-spectrum antimicrobial efficacy against gram-positive and gram-negative bacteria, fungi, persister cells, and spores, and can show a 7 log colony reduction within 2 minutes.1,2

Protect and Defend against SSI

The sterile gel creates a protective superhydrophilic layer that prevents surface attachment of free-floating bacteria while the Xbio technology eliminates pathogens in the gel3. The gel formulation quickly conforms to the wound-bed on and around the surgical site and maintains a consistent barrier that can defend against recolonization for up to 72 hours.3


SurgX is non-toxic and is compatible with a broad range of dressings*. It provides a protective, moist environment that safely facilitates natural healing.

SurgX Mechanism of Action

View the technology and results in our webinar presented by Next Science CTO, Dr. Matthew Myntti

SurgX with Xbio Technology Provides Broad Spectrum Planktonic Efficacy within the Gel

Suspension Time Kill Testing (2 minutes)2

Provides up to 7 log planktonic efficacy within the gel

SurgX with Xbio Technology Prevents Bacterial Adhesion without Maceration Through the Formation of an Oxygen Permeable Superhydrophilic Surface3

SurgX v. Control: ~107 Bacterial Barrier Testing Results

The SurgX barrier offers a unique mechanism with sustained antimicrobial effects. Testing confirms bacteria are unable to migrate through or proliferate within the presents of SurgX3

SurgX Sterile Antimicrobial Gel Brochure


Do not cover with alginate dressings. For External topical use only. Do not ingest. Must not be used in or near the eyes.


SurgX is indicated for the management of post-surgical wounds, stage I-IV pressure ulcers, partial and full-thickness wounds, diabetic foot and leg ulcers, first and second-degree burns, and grafted and donor sites.


SurgX should not be used if there is a history of allergy to any of the ingredients.


Benzalkonium chloride 0.13%, polyethylene glycol 400, polyethylene glycol 3350, sodium citrate, citric acid, and water.

1. Laboratory testing on file
2. Laboratory testing on file
3. Laboratory testing on file

SurgX availability US only