Resources - Next Science

Our Research

Doctor-Driven, not Marketing-Made

Evidence that earns trust, not just attention, Next Science products have been studied and referenced by name and/or concentration in many peer-reviewed publications such as the Journal of Arthroplasty, Surgical Technology International, the Journal of Orthopaedic Experience & Innovation, and others.

mdpi

Advances in Orthopedic Surgery Irrigation: A Review of Traditional Agents and the Emergence of Citrate-Based Solutions. May 2025.

J Orthopaedic Experience & Innovation

The Use of a Novel Surgical Irrigant May Be Associated with Decreased Incidence of Surgical Site Infections. Oct 2024

J Orthopaedic Experience & Innovation

Beneficial effects of a novel intraoperative surgical irrigant on post-operative knee swelling and limb function in primary total knee arthroplasty. Dec 2023.

Mycoses

Efficacy of Biofilm Disrupters against Candida auris and Other Candida Species in Monomicrobial and Polymicrobial Biofilms. Dec 2023.

Wounds

Clinical Assessment of a Biofilm-Disrupting Agent for the Management of Chronic Wounds Compared With Standard of Care: A Therapeutic Approach. May 2018.

Journal of Wound Care

Evaluation of the combination of a biofilm-disrupting agent and negative pressure wound therapy: a case series. Jan 2021.

Diagnostics

A Diagnostic-Driven Prospective Clinical Study Evaluating the Combination of an Antibiofilm Agent and Negative Pressure Wound Therapy. Apr 2024.

Italian Journal of Dermatology and Venereology

Intralesional Anti-Biofilm Therapy for Tunnels in Patients with Hidradenitis Suppurativa. Oct 2021.

Journal of the American Academy of Dermatology

Minimally Invasive Procedure for Hidradenitis Suppurativa Using Antimicrobial Wound Gel Resolves Tunnels, Reverses Microbial Dysbiosis, Decreases Inflammation, and Improves Quality of Life: Prospective, Single-Center, Single-Arm Trial. Jun 2025.

Surgical Infections

Real World Evidence of the Impact of a Novel Surgical Irrigant on Surgical Site Infections in Primary Total Knee Arthroplasty Performed at an Ambulatory Surgery Center. Apr 2024.

Orthopaedic Surgery

Efficacy of a Novel Intraoperative Surgical Irrigant in Preventing Periprosthetic Joint Infections in Primary Knee, Hip, and Shoulder Arthroplasties: A Retrospective Analysis. Apr 2024.

Journal of Arthroplasty

A Novel Irrigant to Eliminate Planktonic Bacteria and Eradicate Biofilm Superstructure With Persistent Effect During Total Hip Arthroplasty. Feb 2022.

Antimicrobial Agents and Chemotherapy

Next Science Wound Gel Technology, a Novel Agent That Inhibits Biofilm Development by Gram-Positive and Gram-Negative Wound Pathogens. Jun 2014.

Wounds

The Effect of a Biofilm-disrupting Wound Gel vs. a Broad-spectrum Antimicrobial Ointment on a Chronic Wound Microbiome: A Secondary Analysis Associating Clinical and Laboratory Findings. Dec 2022.

Journal of Wound Care

Disrupting the biofilm matrix improves wound healing outcomes. Aug 2015.

Curated Content for Busy Doctors

What Fellow Healthcare Professionals Are Listening To, Watching, and Discussing

Podcasts worth a play

The Ortho Show with Dr. Scott Sigman

Journey to Zero, Ravi Bashyal, The Ortho Show with Dr. Scott Sigman

The Ortho Show with Dr. Scott Sigman

Spotlight on Infection, Dr. Andrew Wickline, The Ortho Show with Dr. Scott Sigman

Our Resources

Real Science, On Call

When you want the “why,” not just the “what,” contact our Medical Science Liaisons, PhD-level science support dedicated to clinicians. Experts in cell/microbiology, chemistry, molecular biology, and biomaterials, they’ve published, practiced, and partnered with doctors like you. Whether you have a question about wound management, need data on outcomes, or want help evaluating a tricky case, they’ve been in the research trenches, hospitals, clinics, and bedside. Think of them as your personal scientific bench built to back your expertise—not slow you down.